Translational rodent ERP analysis
Performed all analysis on ERPs collected from rats administered the compound, determining which signals translate across species.
What
Analysis of rodent ERP recordings collected by a contract research organization for Alto. The work compared drug-related responses with measurements used in human studies.
Why it mattered
The comparison helped the team assess which preclinical signals were relevant to its human trials.
My role
Performed the preprocessing, ERP extraction, feature comparisons, effect-size calculations, and statistical analysis.
Outcome
First author on the SOBP 2025 poster describing ERP and time-frequency responses to MK-801 and ALTO-101 in the preclinical study.
Assets
poster
Poster, SOBP 2025 — Translational utility of ERP and time-frequency features for CIAS: preclinical evaluation of MK-801 deficits and rescue by ALTO-101
2025-04